Abstract
Objective: Placenta accreta spectrum disorder(PAS) is a wide spectrum of
disease defining adherence of placenta. In the literature, the
definition of PAS it s still changing after new studies. Design: Despite
the definition is still changing, the exact pathophysiology is not
clear. Setting and population: Pathology reports of all patients who had
undergone peripartum hysterectomy in Sanliurfa Training and Research
Hospital with the diagnosis of PAS, were evaluated retrospectively.
Methods: Diagnosis of PAS was made preoperatively according to the
findings with sonography or MRI from May 2017 to September 2021. Main
outcome measures: Pathology reports of hysterectomy specimens and
comparison of pre and postoperative diagnosis of PAS were the main
outcome measures. Results: A total of 45 cases of peripartum
hysterectomy due to PAS were identified retrospectively during these
four years from the hospital’s medical records. Only 17 of 45 patients
who underwent hysterectomy with the diagnosis of placenta accreta
spectrum were found to have a histopathological diagnosis that supported
placental invasion. In 20 patients, the histopathological diagnosis was
consistent with a normal placenta protruding from a uterine wall defect
independent of placental invasion. Histopathological diagnosis was
compatible with the normal placenta in 8 patients. Conclusion: Although
PAS is defined as ‘anormal placentation’; in new studies myometrial
defect and placental protrusion may be the main cause of PAS. Funding:
None.