Figure 1: A. Illustration of Ab(IgG)
purification using conjugated micellar aggregates. Target IgG + BSA are
captured by micellar aggregates comprised of a non-ionic detergent,
amphiphilic chelator (e.g. bathophenanthroline, (batho)) and
Fe2+ ions. Pure IgG is obtained by extracting IgG’s
bound to the micellar aggregates under conditions that do not co-extract
BSA or dissociate the detergent aggregates. B. Chemical
structure of the non-ionic detergents. The sum of the values represented
by the letters: W, X, Y, Z in the Tween-family is ~ 20.
The number of carbons comprising the hydrophobic anchor of: Tween-20,
40, 60 and 80, are indicated, respectively.