Figure 1. Heatmap of Post hoc Tukey’s HDS test results. A Tukey’s multiple comparisons test was performed to compare potassium between all groups. Euclidean distance and average linkage was used for clustering process. The test results were pre-processed using k-means before applying clustering and gener- ating the heatmap and the dendogram. All test results were transformed for the analysis in Z-score intensity signal. Z score is constructed by taking the ratio of weighted mean difference and combined standard de- viation according to Box and Tiao (1992). The application of a classical method of data normalization, z-score transformation, provides a way of standardizing data across a wide range of experiments. [Table 4 about here.] At binary logistic regression, the OR for patients with SARS-CoV-2 to present with hypokalemia at admission to the ED is twice than the one for non-infected patients (Table 5). At multivariable logistic regression, adjusting for age and sex, the probability to be admitted to the ED with hypokalemia was nearly three times higher for patients with SARS-CoV-2 infection (OR 2.75, 95% CI 1.8-4.1 p<0.001) (Figure 2). For women, the probability to be admitted to the ED with hypokalemia, adjusting for SARS-CoV-2 positivity and age, is more than twice than the one for men (OR 2.43, 95% CI 1.67-3.54 p<0.001) (Figure 2). [Table 5 about here.] Sex differences in electrolyte imbalances caused by SARS-CoV2: a case-control study