Acknowledgments
This research was funded by the National Natural Science Foundation of
China (No.81770569 and 81870421) and the Postdoctoral Science Foundation
of China (2018M643871). K.S.S., S.Y.M., S.Y.T. and performed the
experiments, analyzed the data, and drafted the manuscript; B.L., X.Z.,
and X.H.Z. were responsible for the clinical data acquisition; M.Z. and
Y.S.L. participated in the research design and experiments; and X.M.Z.,
L.W., and Y.H. contributed to critical revision of the manuscript for
important intellectual content.