Figure legends.
Figure 1 . Distribution of fasting plasma concentrations of PCSK9 in 134 pregnant women . Levels of PCSK9 were measured using a sandwich ELISA in plasma samples obtained after women fasted overnight; see Subjects and Methods for details.
Figure 2. Box plot showing exposure to PM10, PM2.5, and NO2.Exposure was evaluated as the mean from one week before the visit (week 0–1) and 12 weeks earlier (week 0–12). PM10, PM2.5, and NO2 were averaged over mean daily concentrations.
Figure 3 . Interaction effect of PM2.5 and PCSK9 levels on gestational age . Strength of association between PCSK9 and gestational age at four selected levels of PM2.5 (25°, 50°, 75°, and 95° percentile). Estimates were calculated from multivariate models adjusted for birth mode (spontaneous, urgent, and elective cesarean) and interaction between PCSK9 and PM2.5 at 0–10 weeks; the P-value for the interaction term was = 0.0258. Adjusted β regression coefficients are reported for 1 mg/m3 increase in PCSK9 concentration.
Table 1. Clinical characteristics of the pregnant women and newborns