BACKGROUND AND PURPOSE
The use of human intestinal alkaline phosphatase (IAP) has already been validated as a novel treatment for endotoxin lipopolysaccharide (LPS)-induced inflammatory diseases, which is mediated through IAP’ s ability to detoxify LPS. However, there has been little investigation into the full extent of IAP’ s physiological function. This study investigates IAP’s non-LPS related functions and clinical applications.