Statistical analysis
Statistical analysis was carried out using software GraphPad Prism 6.01. Quantitative data were expressed as mean ± standart deviation (SD). For comparison between groups of patients and of healthy volunteers, the Mann-Whitney U test for continuous variables for 2-group comparisons was used. Fisher’s exact test was used for the analysis of data also. Odds ratio (OR) and 95% confidence interval (CI) were calculated. The Spearman correlation was used to analyze the relativeness of the study parameters. Statistical significance was considered as p<0.05.