Overlap of genomic divergence and association mapping
The range-wide F ST values that were mapped to the
male Pacific lamprey genome were plotted by genomic position with the
subset of SNPs used in the association testing for the two traits with
consistent strong associations (i.e. adult total body length as measured
at Bonneville Dam “T_BON” and female gonad size as measured at
Willamette Falls “WFA♀”; Fig. 2a,b). For chromosomes 01 and 02, the
adjusted -LOG10(P) values from the association tests were highly
correlated with the genomic divergence as measured byF ST for the female gonad size and adult body size
traits, respectively (Fig. 2a,b). We quantified the overlap of genomic
divergence and trait association by regressing range-wideF ST and the adjusted -LOG10(P) values for the 302
SNPs in the GT-seq panel. These 302 SNPs show positive linear trends for
both traits, but the linear trends with highest slope and
R2 were observed for SNPs on chromosomes 01 and 02 for
the gonad size and body length traits, respectively (Fig. S4). These
results suggest that the high geographic divergence exhibited by SNPs on
chromosomes 01 and 02 may be related to selection on the traits with
which these same SNPs are highly associated.