Note: Genomic intervals that bound the F SToutlier loci on four chromsomes were used to compile a list of genes from the corresponding homologous regions in the sea lamprey genome. For each chromosome’s genomic interval, the annotated genes are listed and were used to generate the functional “terms” based on the FishEnrichr phenotypes “FishEnrichr Phenotype AutoRIF Predicted Z-score” and Fisher’s exact tests for enrichment. The table includes “overlap” of each term with the input gene list, “P-value” from Fisher’s exact test, “Adjusted P-value” using the Benjamini-Hochberg method for correction for multiple hypotheses testing, “Z-score” deviation from expected rank, “Combined Score” is combination of p-value and the z-score, and “Genes” from the enrichment tests that were identified as enriched for a particular term. The top ten terms are listed and sorted by lowest to highest “Z-score”.
Supplemental Materials