Acknowledgements
The authors have no competing financial interests.
We would like to thank Professor Antony Galione, Department of Pharmacology, University of Oxford, for helpful discussions; and Kiera Jamison, for the co-production of Fig. 1.
Correspondence should be addressed to Dr Paula Heister (ph535@cam.ac.uk) or Dr Robin Poston (r.poston@qmul.ac.uk).