HbA1c and renal failure
A recent prospective study reported that acute renal failure is one of
the most common complications in the post-CABG in diabetic
patients50. Compared with diabetic patients with HbA1c
≤ 7%, those with HbA1c > 7% had more incidence of renal
failure (10% vs. 0%) 47. Additionally, the results
of recent meta-analysis, involving nine studies (n = 5,858), suggested
that a higher preoperative HbA1c level was associated with a high risk
of renal failure after cardiac surgery (OR = 1.63, 95% CI
1.13-2.33, p = 0.47, and I 2 = 0%)48. Furthermore, by using receiver operating
characteristic value thresholds, Halkos et al. showed that renal failure
occurred more commonly in patients with elevated HbA1c (threshold 6.7,
odds ratio 2.1) 20. It is worth noting that the 6.7
threshold derived is the below the 7% glycaemic target of the American
Diabetes Association 15.