References
Alho, J. S., Matsuba, C., & Merilä, J. (2010). Sex reversal and primary
sex ratios in the common frog (Rana temporaria). Molecular
Ecology , 19 (9), 1763–1773. doi:
10.1111/j.1365-294X.2010.04607.x
Bachtrog, D. (2006). A dynamic view of sex chromosome evolution.Current Opinion in Genetics & Development , 16 (6),
578–585. doi: 10.1016/j.gde.2006.10.007
Bachtrog, D., Mank, J. E., Peichel, C. L., Kirkpatrick, M., Otto, S. P.,
Ashmann, T.-L., … Consortium, T. T. of S. (2014). Sex
determination: Why so many ways of doing it? PLoS Biology ,12 (7), e1001899. doi: 10.1371/journal.pbio.1001899
Bernabò, I., Gallo, L., Sperone, E., Tripepi, S., & Brunelli, E.
(2011). Survival, development, and gonadal differentiation in Rana
dalmatina chronically exposed to chlorpyrifos. Journal of
Experimental Zoology Part A: Ecological Genetics and Physiology ,315 (5), 314–327. doi: 10.1002/jez.678
Berset-Brändli, L., Jaquiéry, J., Dubey, S., & Perrin, N. (2006). A
sex-specific marker reveals male heterogamety in European tree frogs.Molecular Biology and Evolution , 23 (6), 1104–1106. doi:
10.1093/molbev/msk011
Bókony, V., Kövér, S., Nemesházi, E., Liker, A., & Székely, T. (2017).
Climate-driven shifts in adult sex ratios via sex reversals: the type of
sex determination matters. Philosophical Transactions of the Royal
Society B: Biological Sciences , 372 , 20160325. doi:
10.1098/rstb.2016.0325
Bókony, V., Üveges, B., Ujhegyi, N., Verebélyi, V., Nemesházi, E.,
Csíkvári, O., & Hettyey, A. (2018). Endocrine disruptors in breeding
ponds and reproductive health of toads in agricultural, urban and
natural landscapes. Science of the Total Environment , 634 ,
1335–1345. doi: 10.1016/j.scitotenv.2018.03.363
Bókony, V., Verebélyi, V., Ujhegyi, N., Mikó, Z., Nemesházi, E.,
Szederkényi, M., … Móricz, Á. M. (2020). Effects of two
little-studied environmental pollutants on early development in anurans.Environmental Pollution , 260 , 114078. doi:
10.1016/j.envpol.2020.114078
Bonfield, J. K., Smith, K. F., & Staden, R. (1995). A new DNA sequence
assembly program. Nucleic Acids Research , 23 (24),
4992–4999. doi: 10.1093/nar/23.24.4992
Boratyn, G. M., Thierry-Mieg, J., Thierry-Mieg, D., Busby, B., &
Madden, T. L. (2019). Magic-BLAST, an accurate RNA-seq aligner for long
and short reads. BMC Bioinformatics , 20 , 405. doi:
10.1186/s12859-019-2996-x
Brans, K. I., Engelen, J. M. T., Souffreau, C., & De Meester, L.
(2018). Urban hot-tubs: local urbanization has profound effects on
average and extreme temperatures in ponds. Landscape and Urban
Planning , 176 (March), 22–29. doi:
10.1016/j.landurbplan.2018.03.013
Brelsford, A., Lavanchy, G., Sermier, R., Rausch, A., & Perrin, N.
(2017). Identifying homomorphic sex chromosomes from wild-caught adults
with limited genomic resources. Molecular Ecology Resources ,17 (4), 752–759. doi: 10.1111/1755-0998.12624
Castañeda Cortés, D. C., Arias Padilla, L. F., Langlois, V. S., Somoza,
G. M., & Fernandino, J. I. (2019). The central nervous system acts as a
transducer of stress-induced masculinization through
corticotropin-releasing hormone B. Development (Cambridge) ,146 (8), dev172866. doi: 10.1242/dev.172866
Chardard, D., Penrad-Mobayed, M., Chesnel, A., Pieau, C., & Dournon, C.
(2004). Thermal sex reversals in amphibians. In N. Valenzuela & V.
Lance (Eds.), Temperature-dependent sex determination in
vertebrates (pp. 59–67). Washington: Smithsonian Books.
Decout, S., Manel, S., Miaud, C., & Luque, S. (2012). Integrative
approach for landscape-based graph connectivity analysis: a case study
with the common frog (Rana temporaria ) in human-dominated
landscapes. Landscape Ecology , 27 (2), 267–279. doi:
10.1007/s10980-011-9694-z
Devlin, R. H., & Nagahama, Y. (2002). Sex determination and sex
differentiation in fish: an overview of genetic, physiological, and
environmental influences. Aquaculture , 208 (3–4),
191–364. doi: 10.1016/S0044-8486(02)00057-1
Edmunds, J. S. G., McCarthy, R. A., & Ramsdell, J. S. (2000). Permanent
and functional male-to-female sex reversal in d-rR strain medaka(Oryzias latipes) following egg microinjection of o,p’-DDT.Environmental Health Perspectives , 108 (3), 219–224. doi:
10.1289/ehp.00108219
Eggert, C. (2004). Sex determination: the amphibian models.Reproduction Nutrition Development , 44 (6), 539–549. doi:
10.1051/rnd:2004062
Ezaz, T., Stiglec, R., Veyrunes, F., & Marshall Graves, J. A. (2006).
Relationships between vertebrate ZW and XY sex chromosome systems.Current Biology , 16 (17), R736–R743. doi:
10.1016/j.cub.2006.08.021
Fernandino, J. I., Hattori, R. S., Moreno Acosta, O. D., Strüssmann, C.
A., & Somoza, G. M. (2013). Environmental stress-induced testis
differentiation: Androgen as a by-product of cortisol inactivation.General and Comparative Endocrinology , 192 , 36–44. doi:
10.1016/j.ygcen.2013.05.024
Fridolfsson, A.-K., & Ellegren, H. (1999). A simple and universal
method for molecular sexing of non-ratite birds. Journal of Avian
Biology , 30 (1), 116–121.
Griffiths, R., & Tiwari, B. (1993). Primers for the differential
amplification of the sex‐determining region Y gene in a range of mammal
species. Molecular Ecology , 2 (6), 405–406. doi:
10.1111/j.1365-294X.1993.tb00034.x
Hadidi, S., Glenney, G. W., Welch, T. J., Silverstein, J. T., & Wiens,
G. D. (2008). Spleen size predicts resistance of rainbow trout toFlavobacterium psychrophilum challenge. The Journal of
Immunology , 180 (6), 4156–4165. doi: 10.4049/jimmunol.180.6.4156
Harris, C. A., Hamilton, P. B., Runnalls, T. J., Vinciotti, V., Henshaw,
A., Hodgson, D., … Sumpter, J. P. (2011). The consequences of
feminization in breeding groups of wild fish. Environmental Health
Perspectives , 119 (3), 306–311. doi: 10.1289/ehp.1002555
Hayes, T., Haston, K., Tsui, M., Hoang, A., Haeffele, C., & Vonk, A.
(2002). Feminization of male frogs in the wild. Nature ,419 , 895–896.
Holleley, C. E., O’Meally, D., Sarre, S. D., Marshall-Graves, J. A.,
Ezaz, T., Matsubara, K., … Georges, A. (2015). Sex reversal
triggers the rapid transition from genetic to temperature-dependent sex.Nature , 523 , 79–82. doi: 10.1038/nature14574
Holleley, C. E., Sarre, S. D., O’Meally, D., & Georges, A. (2016). Sex
reversal in reptiles: reproductive oddity or powerful driver of
evolutionary change? Sexual Development , 10 (5–6),
279–287. doi: 10.1159/000450972
Jeffries, D. L., Lavanchy, G., Sermier, R., Sredl, M. J., Miura, I.,
Borzée, A., … Perrin, N. (2018). A rapid rate of sex-chromosome
turnover and non-random transitions in true frogs. Nature
Communications , 9 (1), 4088. doi: 10.1038/s41467-018-06517-2
Kaya, U., Kuzmin, S., Sparreboom, M., Ugurtas, I. H., Tarkhnishvili, D.,
Anderson, S., … Tejedo, M. (2009). Rana dalmatina .The IUCN Red List of Threatened Species , e.T58584A11790570. doi:
https://dx.doi.org/10.2305/IUCN.UK.2009.RLTS.T58584A11790570.en
Kloas, W., Lutz, I., & Einspanier, R. (1999). Amphibians as a model to
study endocrine disruptors: II. Estrogenic activity of environmental
chemicals in vitro and in vivo. Science of the Total Environment ,225 (1–2), 59–68. doi: 10.1016/S0048-9697(99)80017-5
Kosmidis, I. (2019). brglm (0.6.2.) . Retrieved from
https://github.com/ikosmidis/brglm
Lambert, M. R. (2015). Clover root exudate produces male-biased sex
ratios and accelerates male metamorphic timing in wood frogs.Royal Society Open Science , 2 (12). doi:
10.1098/rsos.150433
Lambert, M. R., Skelly, D. K., & Ezaz, T. (2016). Sex-linked markers in
the North American green frog (Rana clamitans ) developed using
DArTseq provide early insight into sex chromosome evolution. BMC
Genomics , 17 (1), 844. doi: 10.1186/s12864-016-3209-x
Lambert, M. R., Smylie, M. S., Roman, A. J., Freidenburg, L. K., &
Skelly, D. K. (2018). Sexual and somatic development of wood frog
tadpoles along a thermal gradient. Journal of Experimental Zoology
Part A: Ecological and Integrative Physiology , (April), 1–8. doi:
10.1002/jez.2172
Lambert, M. R., Tran, T., Kilian, A., Ezaz, T., & Skelly, D. K. (2019).
Molecular evidence for sex reversal in wild populations of green frogs(Rana clamitans) . PeerJ , 7 , e6449. doi:
10.7717/peerj.6449
Liu, J., Huang, S., Sun, M., Liu, S., Liu, Y., Wang, W., … Hua,
W. (2012). An improved allele-specific PCR primer design method for SNP
marker analysis and its application. Plant Methods , 8 , 34.
doi: 10.1186/1746-4811-8-34
Ma, W. J., Rodrigues, N., Sermier, R., Brelsford, A., & Perrin, N.
(2016). Dmrt1 polymorphism covaries with sex-determination patterns inRana temporaria . Ecology and Evolution , 6 (15),
5107–5117. doi: 10.1002/ece3.2209
McCoy, K. A., Amato, C. M., Guillette, L. J., & St. Mary, C. M. (2017).
Giant toads (Rhinella marina ) living in agricultural areas have
altered spermatogenesis. Science of the Total Environment ,609 , 1230–1237. doi: 10.1016/j.scitotenv.2017.07.185
Miura, I. (2017). Sex Determination and sex chromosomes in Amphibia.Sexual Development , 8526 , 298–306. doi: 10.1159/000485270
Nakamura, M. (2013). Is a sex-determining gene(s) necessary for
sex-determination in amphibians? Steroid hormones may be the key factor.Sexual Development , 7 (1–3), 104–114. doi:
10.1159/000339661
Ogielska, M., & Kotusz, A. (2004). Pattern and rate of ovary
differentiation with reference to somatic development in anuran
amphibians. Journal of Morphology , 259 (1), 41–54. doi:
10.1002/jmor.10162
Oike, A., Watanabe, K., Min, M.-S., Tojo, K., Kumagai, M., Kimoto, Y.,
… Nakamura, M. (2017). Origin of sex chromosomes in six groups ofRana rugosa frogs inferred from a sex-linked DNA marker.Journal of Experimental Zoology Part A: Ecological and Integrative
Physiology , 327 (7), 444–452. doi: 10.1002/jez.2130
Olmstead, A. W., Lindberg-Livingston, A., & Degitz, S. J. (2010).
Genotyping sex in the amphibian, Xenopus (Silurana) tropicalis, for
endocrine disruptor bioassays. Aquatic Toxicology , 98 (1),
60–66. doi: 10.1016/j.aquatox.2010.01.012
Orton, F., & Routledge, E. (2011). Agricultural intensity in ovo
affects growth, metamorphic development and sexual differentiation in
the Common toad (Bufo bufo) . Ecotoxicology , 20 (4),
901–911. doi: 10.1007/s10646-011-0658-5
Orton, F., & Tyler, C. R. (2015). Do hormone-modulating chemicals
impact on reproduction and development of wild amphibians?Biological Reviews , 90 (4), 1100–1117. doi:
10.1111/brv.12147
Ospina-Álvarez, N., & Piferrer, F. (2008). Temperature-dependent sex
determination in fish revisited: Prevalence, a single sex ratio response
pattern, and possible effects of climate change. PLoS ONE ,3 (7), 2–4. doi: 10.1371/journal.pone.0002837
Perrin, N. (2009). Sex reversal: a fountain of youth for sex
chromosomes? Evolution , 63 (12), 3043–3049. doi:
10.1111/j.l558-5646.2009.00837.x
Perrin, N. (2016). Random sex determination: When developmental noise
tips the sex balance. BioEssays , 38 (12), 1218–1226. doi:
10.1002/bies.201600093
Phillips, B. C., Rodrigues, N., Jansen van Rensburg, A., & Perrin, N.
(2020). Phylogeography, more than elevation, accounts for sex chromosome
differentiation in Swiss populations of the common frog (Rana
temporaria). Evolution , 74 (3), 644–654. doi:
10.1111/evo.13860
Pinheiro, J., & Bates, D. (2019). R Package “nlme.”
Pyron, A. R., & Wiens, J. J. (2011). A large-scale phylogeny of
Amphibia including over 2800 species, and a revised classification of
extant frogs, salamanders, and caecilians. Molecular Phylogenetics
and Evolution , 61 (2), 543–583. doi: 10.1016/j.ympev.2011.06.012
Quinn, A. E., Sarre, S. D., Ezaz, T., Marshall Graves, J. a, & Georges,
A. (2011). Evolutionary transitions between mechanisms of sex
determination in vertebrates. Biology Letters , 7 (3),
443–448. doi: 10.1098/rsbl.2010.1126
R Core Team. (2019). R: A language and environment for statistical
computing. R ver. 3.5.2. R Foundation for Statistical Computing,
Vienna, Austria. http://www.r-project.org.
Reading, C. J., & Clarke, R. T. (1995). The effects of density,
rainfall and environmental temperature on body condition and fecundity
in the common toad, Bufo bufo . Oecologia , 102 (4),
453–459. doi: 10.1007/BF00341357
Reeder, A. L., Foley, G. L., Nichols, D. K., Hansen, L. G., Wikoff, B.,
Faeh, S., … Beasley, V. R. (1998). Forms and prevalence of
intersexuality and effects of environmental contaminants on sexuality in
cricket frogs (Acris crepitans) . Environmental Health
Perspectives , 106 (5), 261–266. doi: 10.1289/ehp.98106261
Rodrigues, N., Merilä, J., Patrelle, C., & Perrin, N. (2014).
Geographic variation in sex-chromosome differentiation in the common
frog (Rana temporaria). Molecular Ecology , 23 (14),
3409–3418. doi: 10.1111/mec.12829
Rodrigues, N., Studer, T., Dufresnes, C., Ma, W.-J., Veltsos, P., &
Perrin, N. (2017). Dmrt1 polymorphism and sex-chromosome differentiation
in Rana temporaria. Molecular Ecology , 26 (19), 4897–4905.
doi: 10.1111/mec.14222
Rodrigues, N., Vuille, Y., Loman, J., & Perrin, N. (2015).
Sex-chromosome differentiation and “sex races” in the common frog
(Rana temporaria). Proceedings of the Royal Society B: Biological
Sciences , 282 (1806), 20142726. doi: 10.1098/rspb.2014.2726
Sarre, S. D., Ezaz, T., & Georges, A. (2011). Transitions between
sex-determining systems in reptiles and amphibians. Annual Review
of Genomics and Human Genetics , 12 (1), 391–406. doi:
10.1146/annurev-genom-082410-101518
Senior, A. M., Nat Lim, J., & Nakagawa, S. (2012). The fitness
consequences of environmental sex reversal in fish: a quantitative
review. Biological Reviews , 87 (4), 900–911. doi:
10.1111/j.1469-185X.2012.00230.x
Shao, C., Li, Q., Chen, S., Zhang, P., Jinmin, L., Hu, Q., …
Zhang, G. (2014). Epigenetic modification and inheritance in sexual
reversal of fish. Genome Research , 24 (4), 604–615. doi:
10.1101/gr.162172.113.604
Shaw, C. N., Wilson, P. J., & White, B. N. (2003). A reliable molecular
method of gender determination for mammals. Journal of Mammalogy ,84 (1), 123–128. doi:
10.1644/1545-1542(2003)084<0123:ARMMOG>2.0.CO;2
Skelly, D. K., Bolden, S. R., & Dion, K. B. (2010). Intersex frogs
concentrated in suburban and urban landscapes. EcoHealth ,7 (3), 374–379. doi: 10.1007/s10393-010-0348-4
Spasić-Bošković, O., Tanić, N., Blagojević, J., & Vujošević, M. (1997).
Comparative cytogenetic analysis of European brown frogs: Rana
temporaria , R. dalmatina and R. graeca .Caryologia , 50 (2), 139–149. doi:
10.1080/00087114.1997.10797393
Stöck, M., Croll, D., Dumas, Z., Biollay, S., Wang, J., & Perrin, N.
(2011). A cryptic heterogametic transition revealed by sex-linked DNA
markers in Palearctic green toads. Journal of Evolutionary
Biology , 24 (5), 1064–1070. doi:
10.1111/j.1420-9101.2011.02239.x
Stöck, M., Savary, R., Betto-Colliard, C., Biollay, S., Jourdan-Pineau,
H., & Perrin, N. (2013). Low rates of X-Y recombination, not turnovers,
account for homomorphic sex chromosomes in several diploid species of
Palearctic green toads (Bufo viridis subgroup). Journal of
Evolutionary Biology , 26 (3), 674–682. doi: 10.1111/jeb.12086
Tamschick, S., Rozenblut-Kościsty, B., Ogielska, M., Lehmann, A.,
Lymberakis, P., Hoffmann, F., … Stöck, M. (2016). Sex reversal
assessments reveal different vulnerability to endocrine disruption
between deeply diverged anuran lineages. Scientific Reports ,6 , 23825. doi: 10.1038/srep23825
Üveges, B., Mahr, K., Szederkényi, M., Bókony, V., Hoi, H., & Hettyey,
A. (2016). Experimental evidence for beneficial effects of projected
climate change on hibernating amphibians. Scientific Reports ,6 , 26754. doi: 10.1038/srep26754
Vági, B., & Hettyey, A. (2016). Intraspecific and interspecific
competition for mates: Rana temporaria males are effective satyrs
of Rana dalmatina females. Behavioral Ecology and
Sociobiology , 70 (9), 1477–1484. doi: 10.1007/s00265-016-2156-5
van Doorn, G. S., & Kirkpatrick, M. (2007). Turnover of sex chromosomes
induced by sexual conflict. Nature , 449 (7164), 909–912.
doi: 10.1038/nature06178
Veltsos, P., Rodrigues, N., Studer, T., Ma, W.-J., Sermier, R.,
Leuenberger, J., & Perrin, N. (2019). No evidence that Y-chromosome
differentiation affects male fitness in a Swiss population of common
frogs. Journal of Evolutionary Biology , 33 (4), 401–409.
doi: 10.1111/jeb.13573
Vences, M., Hauswaldt, J. S., Steinfartz, S., Rupp, O., Goesmann, A.,
Künzel, S., … Smirnov, N. A. (2013). Radically different
phylogeographies and patterns of genetic variation in two European brown
frogs, genus Rana . Molecular Phylogenetics and Evolution ,68 (3), 657–670. doi: 10.1016/j.ympev.2013.04.014
Wedekind, C. (2017). Demographic and genetic consequences of disturbed
sex determination. Philosophical Transactions of the Royal Society
B: Biological Sciences , 372 (1729), 20160326. doi:
10.1098/rstb.2016.0326
Ye, J., Coulouris, G., Zaretskaya, I., Cutcutache, I., Rozen, S., &
Madden, T. L. (2012). Primer-BLAST: a tool to design target-specific
primers for polymerase chain reaction. BMC Bioinformatics ,13 , 134. doi: 10.1186/1471-2105-13-134
Yoshimoto, S., Ikeda, N., Izutsu, Y., Shiba, T., Takamatsu, N., & Ito,
M. (2010). Opposite roles of DMRT1 and its W-linked paralogue, DM-W, in
sexual dimorphism of Xenopus laevis: Implications of a ZZ/ZW-type
sex-determining system. Development , 137 (15), 2519–2526.
doi: 10.1242/dev.048751
Zlotnik, S., Gridi-Papp, M., & Bernal, X. E. (2019). Laryngeal
demasculinization in wild cane toads varies with land use.EcoHealth , 16 (4), 682–693. doi:
10.1007/s10393-019-01447-x