1 |
Hydroxychloroquine sulfate |
Anti-parasitic drug |
NCT04308668,
NCT04316377, NCT04336748, NCT04322123, NCT04261517, NCT04328467,
NCT04325893, NCT04321278, NCT04340349, NCT04321616, NCT04333654,
NCT04330495, NCT04334928, NCT04332835, NCT04318444, NCT04318015,
NCT04328272, NCT04330144, NCT04326725, NCT04328961, NCT04333732,
NCT04338698, NCT04334148, NCT04335552, NCT04303507, NCT04328012,
NCT04303299, NCT04334967, NCT04332991, NCT04329611, NCT04318015,
NCT04328272, NCT04321993, NCT04329832, NCT04328285, NCT04330586,
NCT04340544, NCT04334512, NCT04329923, NCT04334382, NCT04333225,
NCT04335084, NCT04307693, NCT04323631, NCT04331834, NCT04332094,
NCT04329572, NCT04315896, NCT04339816, NCT04336332 |
2 |
Chloroquine |
Anti-parasitic drug |
NCT04333628, NCT04331600,
NCT04328493, NCT04333732, NCT04303507, NCT04286503, NCT04324463,
NCT04323527, NCT04324463, NCT04323527 |
3 |
Azithromycin |
Antibiotic/anti-inflammatory |
NCT04329832,
NCT04334512, NCT04334382, NCT04332094, NCT04329572, NCT04339816,
NCT04336332, NCT04339426, NCT04328272, NCT04338698, NCT04335552,
NCT04332835, NCT04324463, NCT04322396, NCT04321278,
NCT04322123 |
4 |
Remdesivir |
Adenosine nucleotide analogue prodrug having
broad-spectrum antiviral activity against RNA viruses |
NCT04257656,
NCT04302766, NCT04252664, NCT04315948, NCT04323761, NCT04280705,
NCT04321616, NCT04292899, NCT04292730 |
5 |
Lopinavir/ritonavir |
Protease inhibitors |
NCT04276688,
NCT04321174, NCT04307693, NCT04261907 |
6 |
Ribavirin |
A purine nucleoside analog antiviral drug |
NCT04276688 |
7 |
Camostat Mesilate |
Protease inhibitor |
NCT04321096,
NCT04338906 |
8 |
Favipiravir |
Broad spectrum RNA-dependent RNA polymerase (RdRp)
inhibitor of RNA viruses |
NCT04336904, NCT04333589, NCT04310228,
NCT04303299 |
9 |
DAS181 |
It cleaves sialic receptors from the airway epithelium that
acts as entry receptors for influenza A and B viruses |
NCT04324489,
NCT04298060, NCT03808922 |
10 |
Umifenovir |
antiviral |
NCT04254874, NCT04255017 |
11 |
Oseltamivir |
Antiviral that inhibits viral neuraminidase enzyme |
NCT04338698, NCT04303299, NCT04255017, NCT04261270 |
12 |
rhACE2 |
Block viral entry and decrease viral replication;
anti-inflammatory |
NCT04335136 |
13 |
Losartan |
Angiotensin II receptor blocker |
NCT04335123,
NCT04328012, NCT04312009, NCT04311177, NCT04340557 |
14 |
Methylprednisolone |
Glucocorticoid having anti-inflammatory and
immunomodulatory effect |
NCT04329650, NCT04273321, NCT04263402,
NCT04323592, NCT04244591 |
15 |
Ciclesonide |
Glucocorticoid having anti-inflammatory and
immunomodulatory effect |
NCT04330586 |
16 |
Bevacizumab |
A VEGF inhibitor |
NCT04305106,
NCT04275414 |
17 |
Baricitinib |
Janus kinase (JAK1 and JAK2 inhibitor) inhibitor;
anti-inflammatory |
NCT04340232, NCT04320277 |
18 |
Ruxolitinib |
JAK1/2 inhibitor used to treat myelofibrosis |
NCT04337359, NCT04334044, NCT04331665, NCT04338958 |
19 |
Sargramostim |
Sargramostim binds to GM-CSF, that stimulates JAK2
STAT1/STAT3 signal transduction pathway. That increases hemopoietic
cells and neutrophils production |
NCT04326920 |
20 |
Tocilizumab |
A mAb competitive inhibitor of IL-6 & IL-6R binding |
NCT04317092, NCT04330638, NCT04331795, NCT04332094, NCT04320615,
NCT04332913, NCT04335305, NCT04333914, NCT04335071, NCT04310228,
NCT04339712, NCT04306705, NCT04331808 |
21 |
Sarilumab |
A humanized mAb that blocks interleukin-6 (IL-6)
receptor |
NCT04321993, NCT04315298, NCT04327388,
NCT04324073 |
22 |
Anakinra |
Competitively binds with IL-1RI to inhibit elevated IL-1
mediated immune response |
NCT04339712, NCT04339712,
NCT04324021 |
23 |
Thalidomide |
Immunomodulator, suppress TNF-α production |
NCT04273581, NCT04273529 |
24 |
Mavrilimumab |
A humanized mAb that blocks GM-CSF-R, developed to
treat rheumatoid arthritis |
NCT04337216 |
25 |
Meplazumab |
Humanized IgG2 mAb against CD147, have antiviral
activity against SARS-CoV-2 in invitro assays |
NCT04275245 |
26 |
Leronlimab |
A humanized IgG4 mAb that antagonist CCR5 |
NA |
27 |
Nivolumab |
Check point inhibitor, a humanized IgG4 anti-PD1-R mAb |
NCT04333914 |
28 |
Interferon Beta-1B |
Immunomodulator: Reduce production of
pro-inflammatory cytokines, Enhance activity of Treg cells |
NCT04276688 |
29 |
CD24Fc |
Check point inhibitor with anti-inflammatory activity |
NCT04317040 |
30 |
Piclidenoson |
anti-inflammatory |
NCT04333472 |
31 |
Colchicine |
anti-mitotic drug with anti-inflammatory property |
NCT04326790, NCT04328480, NCT04322565, NCT04322682 |
32 |
Tetrandrine |
Ca channel blocker and anti-inflammatory |
NCT04308317 |
33 |
Anti-SARS-CoV-2 convalescent plasma |
Infuse neutralizing
antibodies from SARS-CoV-2 infected persons recovered from COVID-19, to
control viremia and associated symptoms |
NCT04338360, NCT04340050,
NCT04333355, NCT04332380, NCT04332835, NCT04327349, NCT04333251,
NCT04292340 |
34 |
BCG Vaccine |
The trained immunity |
NCT04328441,
NCT04327206 |
35 |
Fingolimod |
Binds to binds to sphingosine-1 phosphate receptor and
blocks egress of T lymphocytes from lymph nodes |
NCT04280588 |
36 |
Naproxen |
Nonsteroidal anti-inflammatory drug (NSAID) |
NCT04325633 |
37 |
Anluohuaxian |
Used to block pulmonary fibrosis and improving lung
function |
NCT04334265 |
38 |
Peginterferon Lambda-1a |
Not known |
NCT04331899 |
39 |
Tranexamic acid |
Lysine analog inhibits activation of plasminogen.
Used to prevent excessive bleeding in trauma patients |
NCT04338074,
NCT04338126 |