Sl. # Name of the drug Mode of action Trial ID
1 Hydroxychloroquine sulfate Anti-parasitic drug NCT04308668, NCT04316377, NCT04336748, NCT04322123, NCT04261517, NCT04328467, NCT04325893, NCT04321278, NCT04340349, NCT04321616, NCT04333654, NCT04330495, NCT04334928, NCT04332835, NCT04318444, NCT04318015, NCT04328272, NCT04330144, NCT04326725, NCT04328961, NCT04333732, NCT04338698, NCT04334148, NCT04335552, NCT04303507, NCT04328012, NCT04303299, NCT04334967, NCT04332991, NCT04329611, NCT04318015, NCT04328272, NCT04321993, NCT04329832, NCT04328285, NCT04330586, NCT04340544, NCT04334512, NCT04329923, NCT04334382, NCT04333225, NCT04335084, NCT04307693, NCT04323631, NCT04331834, NCT04332094, NCT04329572, NCT04315896, NCT04339816, NCT04336332
2 Chloroquine Anti-parasitic drug NCT04333628, NCT04331600, NCT04328493, NCT04333732, NCT04303507, NCT04286503, NCT04324463, NCT04323527, NCT04324463, NCT04323527
3 Azithromycin Antibiotic/anti-inflammatory NCT04329832, NCT04334512, NCT04334382, NCT04332094, NCT04329572, NCT04339816, NCT04336332, NCT04339426, NCT04328272, NCT04338698, NCT04335552, NCT04332835, NCT04324463, NCT04322396, NCT04321278, NCT04322123
4 Remdesivir Adenosine nucleotide analogue prodrug having broad-spectrum antiviral activity against RNA viruses NCT04257656, NCT04302766, NCT04252664, NCT04315948, NCT04323761, NCT04280705, NCT04321616, NCT04292899, NCT04292730
5 Lopinavir/ritonavir Protease inhibitors NCT04276688, NCT04321174, NCT04307693, NCT04261907
6 Ribavirin A purine nucleoside analog antiviral drug NCT04276688
7 Camostat Mesilate Protease inhibitor NCT04321096, NCT04338906
8 Favipiravir Broad spectrum RNA-dependent RNA polymerase (RdRp) inhibitor of RNA viruses NCT04336904, NCT04333589, NCT04310228, NCT04303299
9 DAS181 It cleaves sialic receptors from the airway epithelium that acts as entry receptors for influenza A and B viruses NCT04324489, NCT04298060, NCT03808922
10 Umifenovir antiviral NCT04254874, NCT04255017
11 Oseltamivir Antiviral that inhibits viral neuraminidase enzyme NCT04338698, NCT04303299, NCT04255017, NCT04261270
12 rhACE2 Block viral entry and decrease viral replication; anti-inflammatory NCT04335136
13 Losartan Angiotensin II receptor blocker NCT04335123, NCT04328012, NCT04312009, NCT04311177, NCT04340557
14 Methylprednisolone Glucocorticoid having anti-inflammatory and immunomodulatory effect NCT04329650, NCT04273321, NCT04263402, NCT04323592, NCT04244591
15 Ciclesonide Glucocorticoid having anti-inflammatory and immunomodulatory effect NCT04330586
16 Bevacizumab A VEGF inhibitor NCT04305106, NCT04275414
17 Baricitinib Janus kinase (JAK1 and JAK2 inhibitor) inhibitor; anti-inflammatory NCT04340232, NCT04320277
18 Ruxolitinib JAK1/2 inhibitor used to treat myelofibrosis NCT04337359, NCT04334044, NCT04331665, NCT04338958
19 Sargramostim Sargramostim binds to GM-CSF, that stimulates JAK2 STAT1/STAT3 signal transduction pathway. That increases hemopoietic cells and neutrophils production NCT04326920
20 Tocilizumab A mAb competitive inhibitor of IL-6 & IL-6R binding NCT04317092, NCT04330638, NCT04331795, NCT04332094, NCT04320615, NCT04332913, NCT04335305, NCT04333914, NCT04335071, NCT04310228, NCT04339712, NCT04306705, NCT04331808
21 Sarilumab A humanized mAb that blocks interleukin-6 (IL-6) receptor NCT04321993, NCT04315298, NCT04327388, NCT04324073
22 Anakinra Competitively binds with IL-1RI to inhibit elevated IL-1 mediated immune response NCT04339712, NCT04339712, NCT04324021
23 Thalidomide Immunomodulator, suppress TNF-α production NCT04273581, NCT04273529
24 Mavrilimumab A humanized mAb that blocks GM-CSF-R, developed to treat rheumatoid arthritis NCT04337216
25 Meplazumab Humanized IgG2 mAb against CD147, have antiviral activity against SARS-CoV-2 in invitro assays NCT04275245
26 Leronlimab A humanized IgG4 mAb that antagonist CCR5 NA
27 Nivolumab Check point inhibitor, a humanized IgG4 anti-PD1-R mAb NCT04333914
28 Interferon Beta-1B Immunomodulator: Reduce production of pro-inflammatory cytokines, Enhance activity of Treg cells NCT04276688
29 CD24Fc Check point inhibitor with anti-inflammatory activity NCT04317040
30 Piclidenoson anti-inflammatory NCT04333472
31 Colchicine anti-mitotic drug with anti-inflammatory property NCT04326790, NCT04328480, NCT04322565, NCT04322682
32 Tetrandrine Ca channel blocker and anti-inflammatory NCT04308317
33 Anti-SARS-CoV-2 convalescent plasma Infuse neutralizing antibodies from SARS-CoV-2 infected persons recovered from COVID-19, to control viremia and associated symptoms NCT04338360, NCT04340050, NCT04333355, NCT04332380, NCT04332835, NCT04327349, NCT04333251, NCT04292340
34 BCG Vaccine  The trained immunity NCT04328441, NCT04327206
35 Fingolimod Binds to binds to sphingosine-1 phosphate receptor and blocks egress of T lymphocytes from lymph nodes NCT04280588
36 Naproxen Nonsteroidal anti-inflammatory drug (NSAID) NCT04325633
37 Anluohuaxian Used to block pulmonary fibrosis and improving lung function NCT04334265
38 Peginterferon Lambda-1a Not known NCT04331899
39 Tranexamic acid Lysine analog inhibits activation of plasminogen. Used to prevent excessive bleeding in trauma patients NCT04338074, NCT04338126