Figure 4: Allele-specific expression within the supergene. (A) Volcano plot of allele-specific expression (ASE) for genes with informative SNPs. Aqua dots represent significant instances (edgeR glmQLFtest, FDR < 0.01), with the names of the genes showing the most extreme ASE (|Log2FC| > 3) indicated. (B) UpSet plot showing overlap between genes with significant differential expression (DE, FDR < 0.01) in the SB/SB versus SB/Sb multifactorial-model comparison and those with significant ASE in SB/Sb heterozygotes (context for increased relative expression shown with arrows). Only genes subjected to both types of analysis are included in this plot.