H influenzae & M catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation
Ali Versi1*, Fransiskus Xaverius Ivan2*, Mahmoud I Abdel-Aziz3, Stewart Bates4, John Riley4, Frederic Baribaud5, Nazanin Zounemat Kermani1, Paolo Montuschi6, Sven-Erik Dahlen7, Ratko Djukanovic8, Peter Sterk3, Anke-Hilse Maitland-Van Der Zee3, Sanjay H Chotirmall2, 9, Peter Howarth8, Ian M Adcock1, Kian Fan Chung1, on behalf of U-BIOPRED consortium.
1National Heart & Lung Institute & Data Science Institute, Imperial College London, United Kingdom;2Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore;3Amsterdam University Medical Centers, Department of Respiratory Medicine, University of Amsterdam, Amsterdam, Netherlands;4Respiratory Therapeutic Unit, GSK, Stockley Park, UK;5Janssen Research and Development, High Wycombe, Buckinghamshire, United Kingdom; 6Department of Pharmacology, Catholic University of the Sacred Heart, Rome, Italy;7Centre for Allergy Research, Karolinska Institute, Stockholm, Sweden; 8Faculty of Medicine, Southampton University, Southampton, UK and NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK;9Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
*Equal contribution
Running title : H influenzae and M catarrhalis in severe asthma