Limitations
First, because of the small population and absence of a control group
receiving a traditional PM, the present results cannot be used to assess
any causal relationship between the variables explored. However, this
explorative study allowed the evaluation of the feasibility of an LP
implantation in our clinical setting and in patients with broad clinical
indications. Second, our center had a high volume of LP implantations
and TLEs with experienced operators, which may have led to more
favorable outcomes. The small sample size made it difficult to draw
conclusions regarding the mortality in this population. Therefore,
multicenter registries and studies with a large study population are
essential in the future. Finally, though there were no sign of
reinfection at the 6 months follow up, LP infection may occur at a later
stage. Furthermore, we used available echocardiography, blood cultures,
and clinical symptoms to identify device infection, the diagnosis of
reinfection of the LP may have been missed.