Conclusion
Our analysis shows that in women with interstitial ectopic pregnancy, management with laparoscopic surgery is associated with lower postoperative hospital stay duration and operation time with no difference in terms of blood loss, post and intraoperative complications, and need for blood transfusion.
Further studies especially interventional studies with longer follow up duration and larger sample size are needed to produce more valid results and till that we recommend using laparoscopic surgery if available as it has some advantages over open surgery.
Disclosure of interests: All authors deny any relevant financial, personal, political, intellectual or religious conflicts of interest with regards to this work.
Contribution to authorship: Greg Marchand gathered the idea and reviewed the whole work starting from search to final writing, Ahmed Taher Masoud performed statistical analysis and wrote the statistical part of the results as well as reviewing the writing process, Katelyn Sainz, Ali Azadi, and Kelly Ware searched all databases for possible included studies and screened the retrieved results, Janelle Vallejo, Sienna Anderson, and Alexa King performed the data extraction and risk of bias assessment for included studies, Asya Osborn, and Stacy Ruther wrote the introduction section, Giovanna Brazil wrote the methods section, Kaitlynne Cieminski, and Sophia Hopewell wrote the results section and served as the second team for screening and data extraction of outcomes and baseline tables, Lisa Rials, and Akarshi Brar collected and discussed our results with previous works and research papers.
Details of ethics approval: This Manuscript has been reviewed by the institutional IRB board at Marchand Institute and was found to be exempt from IRB review. (May 2020, IRB#05-2020-084)
Funding: All authors have no disclosures. No authors received any funding for this review.
Conflicts of Interest : Authors declare no conflicts of interest.