Introduction
Laryngeal malignancies constitute 1% of overall and 13% of the head
and neck region malignancies. [1] Principally, laryngeal
malignancies are classified into 2 main groups according to the
histopathological characteristics: Squamous cell carcinoma (SCC) and
non-SCC laryngeal malignancies.[2,3] Also SCC is classified into two
groups according to the pathological features: conventional (classic)
type and variants of SCC (vSCC), whereas vSCC constitutes up to 5% of
all laryngeal malignancies.[3]
Even though there is vast knowledge present in the literature about the
classification and clinical properties of classical type SCC, limited
information about the vSCC challenges physicians during the
treatment.[4] This study aims to provide a clinical and pathological
evaluation of vSCC with a literature review. Our secondary aim is to
compare the preoperative and postoperative pathological results of the
patients with laryngeal SCC.