Statistical analyses
All data values are given as the mean ± standard error of mean (SEM),
unless otherwise stated. Prior to statistical analysis, normality and
outlier tests were conducted. For comparisons between multiple groups of
data, one-way or two-way ANOVA with a 95% confidence interval was used
followed by a post-hoc Tukey’s or Bonferroni’s test for multiple
comparisons. When making direct comparisons between two paired
measurements, a paired, two-tailed Student’s t-test was used.
Statistical analysis for the electrophysiology in theAPPNL-F/NL-F model and the immunofluorescence
data was conducted using GraphPad Prism version 8.0.0 for Windows,
GraphPad Software, San Diego, California USA, graphpad.
All statistical analyses were conducted using the statistical package
Origin Pro 2016 SR1. Statistical significance was accepted wherep < 0.05 (*p < 0.05, ** p<0.01). The “n” are given as the number of
observations and the number of animals used, unless otherwise stated.