Figure 2. BCG’s consensus gene signature (BCG-CGS) and highly
enriched pathways. (A) A heat map of the log2FC of the
gene expression for differentially expressed genes representing BCG’s
consensus gene signature. Upregulated genes have positive
log2FC denoted in red color, and down regulated genes
have negative values for log2FC denoted in blue color.
(B) Core network for BCG-CGS showing highly connected genes in BCG-CGS,
deleting all singleton genes. Nodes are color-coded using a split pie
chart coloring scheme indicating pathway/gene set contribution to each
node from the top 5 most enriched pathways/gene lists. All details about
pathway/gene set ID are found in Table S2 (Supporting Information).