Soy
The cupins Gly m 5 and 6 were suggested as markers for severe allergic
reactions in 30 soy-allergic European patients.270 A
high diagnostic value of the 2S albumin Gly m 8 was reported in
soybean-sensitized Japanese children with and without
symptoms.271 Gly m 8 had an AUC=0.75 for soy allergy
while the values for Gly m 5 and 6 were 0.69 and 0.64, respectively. In
a study on soy allergy diagnostics, Gly m 8 had the highest AUC (0.79),
comparable to skin prick test (0.76) and sIgE to soy extract
(0.77).272 In this study, the cupins Gly m 5 and 6
were related to mild symptoms.