Cashew
In 63 cashew-allergic Greek children, sIgE to the 2S albumin Ana o 3
(AUC=0.97) performed better than extracts for predicting cashew
allergy.281 A markedly greater risk of a positive food
challenge was observed for higher levels of sIgE to the cupins Ana o 1
and 2, and to Ana o 3 in 173 Dutch children with suspected cashew nut
allergy.282 Ana o 3 discriminated between allergic and
tolerant children better than extract-specific IgE with an AUC=0.94
versus 0.78. A 95% probability for a positive cashew challenge was
estimated for Ana o 3-sIgE at 2.0 kU/L.283