Univariate and multivariate analyses for IVIG resistance
In order to investigate the predictive value of pretreatment NLR, PLR and PNI, the present study performed univariate and multivariate analyses. In the univariate analysis, age (p =0.031), platelet (p=0.004), CRP (p <0.001), serum sodium levels (p =0.028), NLR (p =0.003), PLR (p =0.009), and PNI (p <0.001) were significantly associated with IVIG resistance. Furthermore, clinical features for IVIG resistance were also investigated in a multivariate analysis. The results suggested that age (p =0.024), CRP (p =0.006), serum sodium levels (p =0.007), NLR (p =0.008), PLR (p =0.026), and PNI (p =0.001) were still identified as markedly independent parameters for IVIG resistance (Table 3).