Left ventricular parameters
E and A wave velocities were higher in women than in men and E wave tended to decrease with advancing age (p<0.05). E wave deceleration time was increased in older ages and men had higher values than women, showing a significant positive correlation with age and gender (p<0.001 for both). The mean E/A ratios were 1.63±0.49 (18-29 years), 1.43±0.42 (30-39 years), 1.4±0.4 (40-49 years), 1.25±0.44 (≥50 years) (with <0.001 p value for decades) (Figure-1). Table-2 summarizes data regarding the PW Doppler velocities and LAVI according to age and gender.
Septal e’ and lateral e’ waves were higher in the first decades and women had higher levels than men, whereas septal a’ and lateral a’ waves were higher in men and showed a negative correlation with advancing age (all these parameters were statistically significant (p<0.001). Septal s’ and lateral s’ waves tended to decrease with advancing age, showing a negative correlation. Lateral and septal s’ waves were decreased progressively with advancing age. Lateral s’ wave was higher in men whereas septal s’ wave was higher in women.
In four-chamber view, septal and lateral E/e’ ratios were getting higher with increasing age and women had a little bit higher value than men. The average of septal and lateral E/e’ ratio was 6.7±1.3 (18-29 years), 7.6±1.7 (30-39 years), 8.4±2 (40-49 years), 8.9±2.1 (≥50 years) (statistically not significant between decades) (Figure-2).
The intraclass correlation coefficient was obtained and the Bland-Altman plot test was performed to gain better insights into the data quality between two echocardiographers. In our study, the intraclass correlation coefficient value was 0.965 (95% CI: 0.975–0.992; p<0.001) (Figure-3).