Study Population
We conducted a case-control study that enrolled ischemic stroke patients
who underwent stenting for either extracranial or intracranial arterial
stenosis at Beijing Tiantan Hospital, Capital Medical University. The
inclusion criteria encompassed: 1) Confirmed diagnosis of ischemic
cerebrovascular disease accompanied by 70% to 99% stenosis of major
intracranial or extracranial arteries, as evidenced by DSA. 2)
Initiation of a regimen consisting of clopidogrel (75 mg/day) and
aspirin (100 mg/day) at least 5 days prior to enrollment. 3) Successful
acquisition of informed consent. Patients were excluded if they had: 1)
Contraindications to extracranial or intracranial stenting. 2) Known
allergic reactions or contraindications to aspirin, clopidogrel,
heparin, or any anesthetics. 3) Conditions like active peptic ulcer
disease, bleeding tendencies, severe liver or kidney disorders. 4)
Comorbid conditions potentially shortening life expectancy to less than
a year. 5) Concurrent participation in a conflicting study.