Methods
We analyzed 82421 constipated patients and 82421 individuals without
constipation between 1999 and 2013 from the Taiwanese National Health
Insurance Research Database. Analysis of propensity score was utilized
to match age, gender, comorbidities, and medications at a ratio of 1:1.
Besides, multiple Cox regression analysis was performed to evaluate the
adjusted hazard ratio of asthma. Furthermore, sensitivity tests and a
stratified analysis were conducted.