Skin tests
IDT was done with drugs in 0.9% NaCl as recommended by the
EAACI.31 Readings were immediate at 20 minutes and
delayed at 24, 48, and 72 hours, and patients were advised to return to
show any positive responses occurring after the 72 hours. It was
considered a positive result an infiltrated erythema with diameter
>5mm.7 PT was performed according to the
European guidelines7,31 using a concentration of 30%
of the commercialised culprit drug in petrolatum. Reading was performed
according to the European Society of Contact Dermatitis (ESCD), 20 min
after removal of the strips and 48, 72, and 96 hours
later.32