Figure legends
Figure 1 Disease severity, viral load, and viral duration in WH and NWH patients. (A) Disease severity distribution of the two groups during hospitalization. (B) Viral load at hospital admission and midterm in WH and NWH patients. (C) Viral duration in WH and NWH patients. The viral duration was determined as the time from patient’s exposure to other confirmed patients until his/her viral nucleic acid test was negative. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Figure 2 T cell count in peripheral blood from WH and NWH patients. (A) CD3+ T cell count in peripheral blood/μL. (B) CD4+ T cell count in peripheral blood/μL. (C) CD8+ T cell count in peripheral blood/μL. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Supplemental Figure 1 Pulmonary function in WH and NWH patients at different time points . (A) pH. (B) Partial pressure of oxygen (PO2), mmHg. (C) Partial pressure of carbon dioxide(PCO2), mmHg. (D) Fraction of inspiration O2(FIO2), %. (E) Oxygenation index(OI), mmHg. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Supplemental Figure 2 Hepatic function in WH and NWH patients at different time points. (A) Total bilirubin(TBil), μmol/L. (B) Direct bilirubin(DBil), μmol/L. (C) Alanine aminotransferase(ALT), U/L. (D) Glutamic oxalacetic transaminase(AST), U/L. (E) Lactic dehydrogenase(LDH), U/L. (F) Blood urea nitrogen(BUN), mmol/L. (G) Creatinine(Crea), μmol/L. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Supplemental Figure 3 Blood coagulation function in WH and NWH patients at different time points. (A) plasma prothrombin time(PT), s. (B) activated partial thrombin(APTT), s. (C) Fibrinogen(FIB), g/L. (D) D-Dimer, μg/mL. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Supplemental Figure 4 Inflammatory indicators in WH and NWH patients at different time points. (A) Procalcitonin (PCT), ng/mL. (B) C reactive protein(CRP), mg/L. (C) Interleukin-6(IL-6), pg/mL. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.
Supplemental Figure 5 Hemogram in WH and NWH patients at different time points . (A) White blood cell count(WBC), *109/L. (B) Lymphocyte count(Lymph), *109/L. (C) Neutrophil count(Neut), *109/L. (D) Eosinophils count, *109/L. (E) haemoglobin(Hgb), g/L. (F) platelet count(PLT), *109/L. (F) Albumin(ALB), g/L. The data are expressed as the median and IQR. An unpaired t test was used, and P<0.05 was considered significant.