Temporal Trends in Cancer Incidence
Figure 1 shows the infant cancer incidence trends by gender and races from 1975 to 2014. Infant cancer incidence rates experienced a significant increase from 1975 (17.24/100,000) to 2014 (23.8/100,000) with APC 0.68 (CI 0.30-1.06, p<0.05). The cancer incidence rate rose by 38.1% during this period. There were large variations (SD 3.65) during the 40-year period ranging from 17.24/100,000 in 1975 to 34.62/100,000 in 2005. Both males and females had increasing trends with APC 0.77 (p<0.05) and 0.55 (p<0.05) respectively. The increasing trend was not observed in black infants, but significant increasing trends were found in white (APC 0.63, p<0.05) and other races (APC 1.03, p<0.05). The incidence trends in different SEER areas are shown in Figure 2. Among all 9 registries, New Mexico (APC 1.65) had the highest incidence increase over the 40 years period, followed by Utah (APC 0.90 p<0.05) and Detroit (APC 0.85 p<0.05). No increasing trends were noted in other SEER areas. From Figure 3, the increasing incidence trends were only found in Germ cell (APC 2.95, p<0.05), leukemias (APC 1.33, p<0.05) and sarcomas (APC 1.79, p <0.05) . Renal and lymphomas showed a decreasing incidence trend (APC<0), but not significant(p>0.05).