Association of probability of pulmonary hypertension with right chamber fibrosis
The relationship between increased sPAP values and myocardial fibrosis in right chambers was evaluated in our second cohort of postmortem samples biopsies. Clinical and echocardiographic characteristics are presented in supplementary table 1 . sPAP had a positive correlation with right ventricular fibrosis (r= 0.671, 95% CI 0.118-0.906; p=0.024), but not with atrial fibrosis (r= 0.416, 95% CI -0.246 to 0.81; p=0.203), which explains the explained 18.3% and 8.1% of the variability of right ventricular and atrial fibrosis, respectively (Supplementary Figure 3 ).