CONCLUSION
Elevated pulmonary artery pressure is associated with dysfunction of the
right atrium and right ventricle as shown by decreased RV and RA peak
global longitudinal strain. We believe that this chronic dysfunction may
be related to an eventual risk for fibrosis. The use of
echocardiographic derived strain parameters in clinical practice could
be a potential tool for detecting the presence and evaluating the
probability of PH as estimated by sPAP. If validated, proposed cut-off
values may improve the clinical staging of pulmonary hypertension by
including a non-invasive marker of dysfunction or fibrosis.
ACKNOWLEDGMENTS: The authors would like to acknowledge all the
staff of the Nuclear Cardiology Department at Instituto Nacional de
Cardiologia Ignacio Chavez, particularly to the nurses and technicians.
NEAV and ECG are enrolled at the PECEM program of the Faculty of
Medicine, and CONACyT supports them.
CONFLICT OF INTERESTS: The authors declare that they have no
conflict of interests.
AUTHORS’ CONTRIBUTIONS: Research idea and study design NEZ,
NEAV, EAR; data acquisition: RAS, GCC, AAF, DOC; data
analysis/interpretation: NEZ, NEAV, ECG; statistical analysis: NEAV,
ECG; manuscript drafting: NEZ, NEAV, LR, EAR NCN; supervision or
mentorship: NEZ, LR. Each author contributed important intellectual
content during manuscript drafting or revision and accepts
accountability for the overall work by ensuring that questions
pertaining to the accuracy or integrity of any portion of the work are
appropriately investigated and resolved. NEZ, NEAV, LR, RAS, GCC, AAF,
DOC, EAR
FUNDING: No funding was received.