Cellular protrusions of immune cells can also be employed as a therapeutic modality to treat cancer. Weiskopf and Weissman (2015) explored the role of macrophages in antibody therapies for cancer, highlighting their ability to perform antibody-dependent phagocytosis [66]. This process significantly involves the use of filopodia for initial contact and engagement with target cells, emphasizing the critical role of macrophage filopodia in cancer therapies. Pathria, Louis, and Varner (2019) discussed the critical pathways regulating the recruitment, polarization, and metabolism of tumor-associated macrophages (TAMs) during tumor progression. The ability of TAMs to phagocytose tumor cells, a process that involves the use of filopodia, was highlighted as a potential therapeutic strategy [67]. Jaiswal, Chao, Majeti, and Weissman (2010) discussed how macrophages act as mediators of tumor immunosurveillance. They emphasized the role of macrophages in the recognition and phagocytic clearance of cancer cells, a process that involves the dynamic use of filopodia [68].