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Chronic cough in children: the etiology and medical history of 420 cases in Shanghai
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  • Yonghong Jiang,
  • Zhen Xiao,
  • Zhiyan Jiang,
  • Zhoujian Yang,
  • Junxia Li,
  • Liming Mao,
  • Jingwen Gu,
  • YiLiu Chen,
  • Shuqin Wang,
  • SUNGUK JANG
Yonghong Jiang
Long Hua Hospital
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Zhen Xiao
Long Hua Hospital
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Zhiyan Jiang
Long Hua Hospital
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Zhoujian Yang
Pudong New District Hospital of TCM
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Junxia Li
Fengxian District Hospital of TCM
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Liming Mao
Jiading District Hospital of TCM
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Jingwen Gu
Shanghai Seventh People’s Hospital
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YiLiu Chen
Long Hua Hospital
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Shuqin Wang
Long Hua Hospital
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SUNGUK JANG
Long Hua Hospital
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Abstract

Objective: Chronic cough is one of the most common and frequently-occurring diseases in children. We investigated the etiologies and clinical features of children with chronic cough (CC), in order to improve the diagnostic and treatment of the disease by pediatricians. Methods: Participating 420 children, aged 1-14 years old, from 5 hospitals in different regions of Shanghai, between September 2017 and July 2019. Children with chronic cough were enrolled to identify the specific cause and clinical information based on a questionnaire survey. All the data were collected and statistically analyzed by Chi-square test to identify the constituent ratio of each cause. Results: The etiology component ratio showed that 146 cases (34.8%) had PIC; 96 cases (22.9%) had UACS; 90 cases (21.4%) had CVA; 75 cases (17.9%) had AC; 11 cases (2.6%) had TS; 2 cases (0.5%) had GERD. For the children with CC, the mainly age of onset is 3-6 years (54.05%). The mainly cough character is wet cough (65.7%). 67.1% of children with chronic cough were prescribed antibiotics, of which 41.7% were azithromycin. Various cough drops, antihistamines, aerosolized inhalation, montelukast, etc. were often used in the treatment of children’s chronic cough. Conclusion: The leading 3 causes of chronic cough in children were PIC, UACS and CVA. The mainly age of onset is 3-6 years; mainly cough character is wet cough. Antibiotics are the mainly treatment, often combined with cough medicine and atomization.

Peer review status:UNDER REVIEW

08 Jul 2020Submitted to Pediatric Pulmonology
08 Jul 2020Assigned to Editor
08 Jul 2020Submission Checks Completed
12 Jul 2020Reviewer(s) Assigned
26 Jul 2020Review(s) Completed, Editorial Evaluation Pending