All Study cohort Recurrence Recurrence Recurrence AT recurrence AT recurrence AT recurrence AF recurrence AF recurrence AF recurrence AF recurrence Persistent AF recurrence Persistent AF recurrence Persistent AF recurrence
(n=340) (n=191) – (n=136) + (n=55) p – (n=177) + (n=14) p – (n=147) + (n=44) p – (n=165) – (n=165) + (n=26) p
Age (years) 65.1±10.1 65.3±9.9 64.6±9.5 67.2±10.6 0.09 65.0±9.9 70.1±8.7 0.06 65.0±9.6 66.5±10.9 0.37 64.9±9.8 64.9±9.8 68.2±10.5 0.11
Male sex 268 (78.8) 149 (78.0) 108 (79.4) 41 (74.5) 0.45 140 (79.1) 9 (64.3) 0.20 116 (78.9) 33 (75.0) 0.68 128 (77.6) 128 (77.6) 21 (80.8) 0.81
Body mass index (kg/m2) 25.2±3.9 25.0±4.1 25.1±4.2 24,7±4.0 0.57 25.0±4.2 25.4±4.0 0.73 25.1±4.2 24.5±4.0 0.40 25.2±4.2 25.2±4.2 23.7±3.5 0.08
AF duration (months) 3.0 [2.0–12.8] 3.0 [2.0–15.0] 3.0 [2.0–10.3] 6.0 [2.0–35.0] 0.048 3.5 [2.0–19.5] 1.5 [1.0–2.8] <0.01 3.0 [2.0–10.0] 12.0 [2.5–48.0] <0.01 3.0 [2.0–12.0] 3.0 [2.0–12.0] 8.0 [2.0–48.0] 0.04
Hypertension 168 (49.4) 84 (44.0) 63 (46.3) 21 (38.2) 0.34 81 (45.8) 3 (21.4) 0.10 65 (44.2) 19 (43.2) 1.00 72 (43.6) 72 (43.6) 12 (46.2) 0.83
Diabetes 51 (15.0) 28 (14.7) 17 (12.5) 11 (20.0) 0.26 25 (14.1) 3 (21.4) 0.44 19 (12.9) 9 (20.5) 0.23 23 (13.9) 23 (13.9) 5 (19.2) 0.55
Chronic heart failure 40 (11.8) 24 (12.6) 16 (11.8) 8 (14.5) 0.63 20 (11.3) 4 (28.6) 0.08 20 (13.6) 4 (9.1) 0.61 21 (12.7) 21 (12.7) 3 (11.5) 1.00
Prior stroke/TIA 26 (7.7) 17 (8.9) 14 (10.3) 3 (5.5) 0.40 17 (9.6) 0 (0.0) 0.62 14 (9.5) 3 (6.8) 0.77 14 (8.5) 14 (8.5) 3 (11.5) 0.71
LVEF (%) 60.8±10.9 60.6±10.9 60.5±10.7 61.0±11.4 0.77 61.2±10.4 53.6±14.2 0.01 59.9±11.3 63.3±8.8 0.07 60.2±11.3 60.2±11.3 63.2±7.5 0.21
LA diameter (mm) 44.3±6.0 44.1±6.2 43.6±6.3 45.4±6.0 0.07 43.9±6.3 46.5±5.4 0.14 43.9±6.2 45.0±6.2 0.31 44.1±6.3 44.1±6.3 44.5±5.9 0.75
LCPV or RMPV 29 (8.5) 18 (9.4) 12 (8.8) 6 (10.9) 0.79 15 (8.5) 3 (21.4) 0.13 14 (9.5) 4 (9.1) 1.00 16 (9.7) 16 (9.7) 2 (7.7) 1.00
Treatment with AADs 91 (26.8) 47 (24.6) 22 (16.2) 25 (45.5) <0.01 40 (22.6) 7 (50.0) 0.046 27 (18.4) 20 (45.5) <0.01 34 (20.6) 34 (20.6) 13 (50.0) <0.01
Roof line 265 (77.9) 135 (70.7) 101 (74.3) 34 (61.8) 0.11 125 (70.6) 10 (71.4) 1.00 109 (74.1) 26 (59.1) 0.06 123 (74.5) 123 (74.5) 12 (46.2) 0.01
Bottom line 239 (70.3) 135 (70.7) 101 (74.3) 34 (61.8) 0.11 125 (70.6) 10 (71.4) 1.00 109 (74.1) 26 (59.1) 0.06 123 (74.5) 123 (74.5) 12 (46.2) 0.01
Touch up ablation for LAPW isolation 48 (14.1) 31 (16.2) 21 (15.4) 10 (18.2) 0.67 27 (15.3) 4 (28.6) 0.25 23 (15.6) 8 (18.2) 0.65 28 (17.0) 28 (17.0) 3 (11.5) 0.77
CTI ablation 334 (98.2) 186 (97.4) 134 (98.5) 52 (94.5) 0.15 173 (97.7) 13 (92.9) 0.32 144 (97.8) 42 (95.5) 0.33 162 (98.2) 162 (98.2) 24 (92.3) 0.14
MI ablation 131 (38.5) 0 (0.0)