Esophagogastroscopy findings and PAGI-SYM scores
Esophageal lesions, including erythema and erosion, were detected in seven patients (13.0%); however, no ulcerations were observed. GH was confirmed in 10 patients (18.8%). A representative case is shown inFigure 4A .
PAGI-SYM scores (Figures 4B and 4C ) did not significantly differ between patients with and without GH before ablation. In patients with GH, scores significantly increased 1 week after ablation, compared with those before ablation (from 1.0 [0.0–2.8] to 5.0 [3.0–11.0], p<0.01); however, they did not significantly differ between before and 1 day after ablation. At 1 week, 2 weeks, or 3 weeks after ablation, the scores were significantly higher in patients with GH (GH+) than in those without GH (GH–) (1 week: 5.0 [3.0–11.0] vs. 0.0 [0.0–3.0], p<0.01; 2 weeks: 5.0 [2.0–9.0] vs. 0.0 [0.0–3.0], p<0.01; 3 weeks: 3.0 [0.8–5.8] vs. 0.0 [0.0–1.0], p<0.01, respectively). Potential GH-related symptoms resolved within 3 months after ablation in all patients. One patient transiently received a medication for improvement of GH, and no medications other than PPI were prescribed in other patients.