Conclusion
In conclusion, CJD was incurable, irreversible, and had the propensity
to present atypically. It is vital to make an early and prompt diagnosis
based on its clinical features due to its mortality and infectivity. In
this case, the female patient’s clinical manifestations and the course
of the disease were consistent with the diagnostic criteria of the
disease. This patient has not undergone the lumbar puncture or the brain
biopsy. However, the clinical diagnosis will help the family member
prepare palliative care and improve the quality of the rest life of the
patient. With the advent of advanced neuroimaging, the new RT-QuIC
technology, the rate of misdiagnosis of CJD has reduced. However, it was
still critical for the clinician to fully recognize this fatal
neurodegenerative disease and differentiate it from other mimic
diseases, especially in elderly patients, and avoid initiating
inappropriate therapy.