Diagnosis, Treatment and medicine
The basic ways to diagnosis of COVID-19 is that a case from the
infected area, or suspected patient and the types of information have
had from the past of history, and to approach the infection diagnosis we
have some scientific tests will help to identify the infection such as
CT imaging findings, and laboratory tests like (reverse transcriptase
polymerase chain reaction [RT-PCR] tests on respiratory tract
specimens) according to standards of either
the WHO (2020a) or the National Health Commission of China (2020a). The
meaning of a single negative RT-PCR test result from suspected patients
is that the patient does not exclude infection. Because of some
epidemiological history problems we should inform that the case may be
awareness, and also if the suspected case with COVID-19 symptoms it will
be the way to obtain the result and also another way to diagnosis is
that the patient with the positive CT imaging results. And if not there
has been no evidence from randomized controlled trials to recommend any
specific anti-nCoV treatment, so the management of COVID-19 has been
largely supportive (WHO 2020a).
First of all to treatment, Mild illnesses should be treated at home
while maintaining the ill person’s body hydrated, controlling fever and
cough, consuming nutrition, and using antibiotics regularly. It was
suggested by China Oseltamivir Guidelines to avoid antivirals in
short-term treatment; also, corticosteroids could be used in acute
respiratory distress syndrome (ARDS) COVID-19. The WHO has published a
detailed guide for critical care management, which could be updated
according to new findings.There is no fully approved therapy for COVID-
19 yet, although researches are still ongoing. Antiviral drugs, for
example, ribavirin and lopinavir/ritonavir, ( Del Rio and Malani 2020).
were found beneficial based on the experience from SARS and MERS. Before
recommending these drugs, we need more evidence. Further medicines are
suggested for pro treatments, such as chloroquine, arbidol, intravenous
immunoglobulin, plasma, and interferon. in addition to using traditional
Chinese herbs. Grein et al. conducted a study of using remdesivir on 53
patients who received at least one dose of the medication(Amin, Florez
et al. 2018). Basically, 30 patients, 57% of the total number, needed
mechanical ventilation, and 4 patients (8%) have treated with
extracorporeal membrane oxygenation. The follow-up period was 18 days,
where 36 patients (68%) experienced an increase in oxygen support,
including 17 among 30 patients (57%) who received extubated mechanical
ventilation. It was reported that 25 patients (47%) have successfully
recovered, and seven patients (13%), unfortunately, died. Death cases
were 18% (6 out of 34) among patients who received invasive ventilation
and 5% (1 of 19) among those who did not obtain invasive ventilation.In
a study by Shen et al. about administrating blood plasma therapy
obtained from COVID-19 patients who had recovered, 5 patients received
mechanics ventilation. After treated with plasma transfusion, body
temperature became normal in 3 days for 4 out of the 5 patients,
sequential organ failure assessment (SOFA) scores decreased, and PAO2 /
FIO increased in 12 days (range: 172-276 before and 284-366 after).
Viral load also decreased and became negative within 12 days after the
transfusion. From this achievement of their clinical findings, it can be
concluded that the administration of plasma is quite effective, but
because the sample is limited, further clinical trials are needed with a
larger sample size.(Chen, Xiong et al. 2020)