Statistical Analysis
Clinical characteristics, treatments, outcomes, and resource utilization
between salicylate intoxication patients with and without AKI were
compared using student’s t-test for continuous variables, and
Chi-squared test for categorical variables. Clinical characteristics
associated with AKI were identified using multivariable logistic
regression with backward stepwise selection. The association of AKI with
clinical outcomes was evaluated using logistic regression analysis, and
the association of AKI with length of hospital stay and hospitalization
cost was evaluated using linear regression analysis, with pre-specified
adjustment for clinical characteristics. Statistical significance was
achieved when two-tailed p-value <0.05. SPSS statistical
software (version 22.0, IBM Corporation, Armonk, NY, USA) was used for
all analyses.