The Association of Acute Kidney Injury with In-Hospital Treatments, and Outcomes
Salicylate intoxication patients with AKI had higher requirment for non-invasive ventilation support (OR 3.06; p<0.001), invasive mechanical ventilation (OR 3.99; p<0.001), blood component transfusion (OR 2.70; p<0.001), and renal replacement therapy (OR 7.25; p<0.001) than patients without AKI. After adjustment for potential confounding errors, a statistically significant association between development of an AKI with risk of organ failure, including respiratory failure (OR 4.08; p<0.001), circulatory failure (OR 2.76; p<0.001), liver failure (OR 6.30; p<0.001), neurological failure (OR 2.05; p<0.001), hematological failure (OR 3.48; p<0.001) and in-hospital mortality (OR 4.93; p<0.001) (Table 3 ).