Methods
We performed a literature search in PubMed for full-text publications
dealing with retrospective cohort assessments of prescription databases
in Europe, which investigated AIT products from the real-world
perspective. We used the search profile ((desensitization, immunologic
OR sublingual immunotherapy OR subcutaneous immunotherapy) AND
((retrospective database) OR (real world evidence) OR (medication
adherence AND retrospective)) and included all respective publications
until March 31,2022.
Data for long-term effectiveness in allergic rhinitis, allergic asthma,
time to onset of asthma and medication adherence were summarized and
evaluated.