Transplant details and GVHD prophylaxis
Both donor types (related or unrelated) contained matched or mismatched grafts. Graft sources were derived from bone marrow, peripheral blood, or cord blood. All conditioning regimens utilized for the eligible patients involved MAC with 12 or 13.2 Gy of TBI. TBI was administered to the patients in six fractions (two fractions per day). Different GVHD prophylaxis was adopted according to the administered graft source. GVHD prophylaxis for cord blood transplantation (CBT) consists of cyclosporin (CSA) and methylprednisolone. Most GVHD prophylaxis for HCT from the graft of a related donor consisted of CSA and methotrexate (MTX). Prophylaxis for HCT from a graft of an unrelated donor consisted of tacrolimus and MTX.