5 Conclusion
In examining the relation between anatomical features of the ascending aorta and sinus of Valsalva and distribution of LVZs on the anterior LA wall in patients with AF, we found that a relatively small intrathoracic space along with the relatively low BW and BMI might affect the course of the ascending aorta and lead to mechanical compression of the LA. In addition to this anatomical change, distention of the NCC, increased LA pressure, and sinking of the ascending aorta into the anterior LA appear to promote development of LVZs on the anterior LA wall. Progressive remodeling of the anterior LA wall may not be implicated in LA arrhythmogenicity.