5 Conclusion
In examining the relation between anatomical features of the ascending
aorta and sinus of Valsalva and distribution of LVZs on the anterior LA
wall in patients with AF, we found that a relatively small intrathoracic
space along with the relatively low BW and BMI might affect the course
of the ascending aorta and lead to mechanical compression of the LA. In
addition to this anatomical change, distention of the NCC, increased LA
pressure, and sinking of the ascending aorta into the anterior LA appear
to promote development of LVZs on the anterior LA wall. Progressive
remodeling of the anterior LA wall may not be implicated in LA
arrhythmogenicity.