We present a case of obstructive jaundice without biliary stones. This was due to a sclerotrophic gallbladder causing compression (Mirizzi’s syndrome) or adhesions to the extrahepatic biliary tree, pain and recurrent cholecystitis. The jaundice resolved following cholecystectomy. Mirizzi’s syndrome should be suspected in a patient with cholecystitis and obstructive jaundice after a thorough clinical assessment have excluded the usual causes of these symptoms.