Methods
An umbrella literature review and subsequent meta-analysis was
conducted. The protocol was informed by Joanna Briggs Reviewer’s Manual
for
‘Development
of an Umbrella review protocol’ (8) and published on PROSPERO
(CRD42021233398).
Eligibility criteria
Eligible studies were systematic reviews which conducted a meta-analysis
to explore the effect of ACEIs/ARBs on any COVID-19 related clinical
outcomes among adults (≥18 years) with COVID-19 diagnosis.