Supplementary files’ captions and legends
Supplementary file 1. Search
strategy used in the database searches
Supplementary file 2. List and
details of the irrelevant studies excluded at the stage of abstract and
title screening
Supplementary file 3. Study
characterises of the 47 eligible reviews included in the current
umbrella
systematic review
Supplementary file 4. Details of
all the 213 meta-analyses point estimates reported by the eligible 47
reviews and were included in the current study
Supplementary file 5. Quality
assessment score of the 47 eligible reviews included in the current
umbrella systematic review using AMSTAR 2 tool
Supplementary file 6. Forest plot
depicting sub-group analyses pooled estimates for the association
between mortality and ACEIs/ARBs use sub-grouped by A) type of analyses
(crude vs. adjusted); B) peer-review status; C) methodological quality;
and D) hypertension status
Supplementary file 6A. Forest plot depicting sub-group analyses pooled
estimates for the association between mortality and ACEIs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 6B. Forest plot depicting sub-group analyses pooled
estimates for the association between mortality and ARBs use sub-grouped
by A) type of analyses (crude vs. adjusted); B) peer-review status; C)
methodological quality; and D) hypertension status
Supplementary file 7. Forest plot
depicting sub-group analyses pooled estimates for the association
between death/ICU admission (as a composite outcome) and ACEIs/ARBs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 7A. Forest plot depicting sub-group analyses pooled
estimates for the association between death/ICU admission (as a
composite outcome) and ACEIs use sub-grouped by A) type of analyses
(crude vs. adjusted); B) peer-review status; C) methodological quality;
and D) hypertension status
Supplementary file 7B. Forest plot depicting sub-group analyses pooled
estimates for the association between death/ICU admission (as a
composite outcome) and ARBs use sub-grouped by A) type of analyses
(crude vs. adjusted); B) peer-review status; C) methodological quality;
and D) hypertension status
Supplementary file 8. Forest plot
depicting sub-group analyses pooled estimates for the association
between severe COVID-19 and ACEIs/ARBs use sub-grouped by A) type of
analyses (crude vs. adjusted); B) peer-review status; C) methodological
quality; and D) hypertension status
Supplementary file 8A. Forest plot depicting sub-group analyses pooled
estimates for the association between severe COVID-19 and ACEIs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 8B. Forest plot depicting sub-group analyses pooled
estimates for the association between severe COVID-19 and ARBs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 9. Forest plot
depicting sub-group analyses pooled estimates for the association
between hospitalisation and ACEIs/ARBs use sub-grouped by A) type of
analyses (crude vs. adjusted); B) peer-review status; C) methodological
quality; and D) hypertension status
Supplementary file 9A. Forest plot depicting sub-group analyses pooled
estimates for the association between hospitalisation and ACEIs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 9B. Forest plot depicting sub-group analyses pooled
estimates for the association between hospitalisation and ARBs use
sub-grouped by A) type of analyses (crude vs. adjusted); B) peer-review
status; C) methodological quality; and D) hypertension status
Supplementary file 10. Publication
bias funnel plot for the outcomes with >=10 studies
Supplementary file 11. Results of
the influential analyses