Effect of LCZ on the transcriptional levels of inflammatory cytokines of mice mammary tissue
The effect of LCZ on the expression levels of inflammatory cytokines of mice mammary tissue is shown in Figure 8. The expression levels of TNF-α, IL-6, and IL-1β in the E. coli group were significantly up-regulated compared with the LCZ + E. coli group. Significant up-regulation was also observed in the expression levels of IL-1β in the LCZ group compared with the Control group; however, no significant differences were observed in the expression levels of IL-6 and TNF-α.