Introduction
Frozen elephant trunk (FET) has evolved over the years in technology and techniques. The new generation E-vita-Open-NEO (JOTEC CryoLife), is now available in 3 variations. We report first in man implantations from 3 different countries in Asia-Pacific with a note on perioperative coagulation management
The article does not represent a clinical trial or an international multicentre study. It is a direct case reporting reporting of experience and outcomes, henceforth, IRB approvalĀ  was note required. Further informed conset from each of the three patients has has been individually obtained. Moreover, institutional approval for use of Evita-open-NEO (CE market approval, March 2020) has been approved locally by governance boards at every reporting centres.