Refractory
neutrophils and monocytes in patients with inflammatory bowel disease
after repeated bouts of prolonged exercise
Roy Spijkerman 1,2,3, Lillian
Hesselink1,2,
Carlo Bertinetto4, Coen CWG
Bongers 5, Falco Hietbrink1, Nienke
Vrisekoop 2,3, Luke PH Leenen1,
Maria TE Hopman5, Jeroen J Jansen4,
Leo Koenderman2,3.
1 Department of
Trauma Surgery, University Medical Center Utrecht (Heidelberglaan 100,
3584 CX), Utrecht, The Netherlands.
2Center for
Translational Immunology (CTI), University Medical Center Utrecht
(Heidelberglaan 100, 3584 CX), Utrecht, The
Netherlands.
3 Department of
Respiratory Medicine, University Medical Center Utrecht (Heidelberglaan
100, 3584 CX), Utrecht, The
Netherlands
4Institute for
Molecules and Materials (Analytical Chemistry), Radboud University
(Heyendaalseweg 135, 6525 AJ), Nijmegen, The
Netherlands
5Department of
Physiology Radboud Institute for Health Sciences (RIHS), Radboud
university medical center (Geert Grooteplein Zuid 10, 6525 GA),
Nijmegen, The
Netherlands.
Correspondence to:Leo Koenderman, Department of
Respiratory Medicine and Center for Translational Immunology, University
Medical Center Utrecht (Heidelberglaan 100, 3584 CX), Utrecht, The
Netherlands
E-mail: l.koenderman@umcutrecht.nl
Funding: The AQUIOS CL® “load & go” flow
cytometer is provided by the company Beckman Coulter Life Sciences,
Miami, FL, USA. All authors declare that there are no other competing
interests. This article was supported by a grant of the Netherlands
Organization for Scientific Research (NWO) in the framework of the
“Startimpulse Measurement & Detection of healthy behavior” Dutch
National Research Agenda.
Conflicts of interest: All authors declare that they do not
have potential conflicts of interest.