Search Strategy
The systematic review and meta-analysis was reported based on the
guidelines of Preferred Reporting Items for Systematic Reviews and
Meta-Analyses (PRISMA)28. A computerized
literature search was performed from inception to April 2020 using
various databases including PubMed (http://www.pubmed.com), ISI Web of
Science (http://www.webofknowledge.com), Scopus (http://www.scopus.com),
and Google Scholar (http://www.scholar.google.com) search. The following
phrases and their combinations of MeSH and non-MeSH terms were used,
including: “soy protein”, “soybean proteins”, “soy isoflavones”,
“soy”, “isoflavones”, “soy diet replacement”, “meal replacement
therapy”, “adipokines” “adiponectin”, “leptin”, “controlled
trial”, “randomized”, “randomised”, “random”, “randomly”,
“randomized clinical trial”, “RCT”, “blinded”, “double blind”,
“double blinded”, “trial”, “controlled clinical trial”,
“crossover procedure”, “cross-over trial”, “double blind procedure
”and “equivalence trial”. Reference lists of all articles were
examined for identification of further eligible studies.