Decreased macrophage in the spleens after blocking the NF-κb pathway
After using the NF-κb blocker, the total macrophage percentages were lower in the NF-κb blocked (prevent and treated) groups than controls(P<0.01)(Figure 5b). Spleen M1 macrophages in the EAE control group were higher than that in the blocked group(P<0.01), and spleen M2 macrophages were higher in the EAE control group than in the blocked group(P<0.05)(Figure 5b).