Conclusion:
In conclusion our study demonstrated that the SCIT compliance of children is higher than adults. Moving to another city, improvement of symptoms and ineffectiveness are the leading reasons for drop-out. Besides, COVID-19 pandemic significiantly reduced the compliance of AIT, nearly one-third of children, especially in older ages and males. However, we conclude that the drop-outs during the COVID-19 pandemic can be prevented by an effective physician and patient/family communication and, by helping with problems and doubts.
CONFLICT OF INTEREST
All authors declared that there are no conflict of interest and no funding. All authors approved the final version of the manuscript. The study protocol has been approved by the local ethical committee, and all parents/guardians provided written informed consent.
ACKNOWLEDGEMENTS
Special thanks to the pediatric allergy department staff who prepare, coordinate and administer our clinic immunotherapy program and to the medical staff in outlying offices who help administer the program.