Ethics
statement
All applicable animal welfare regulations, including EU Directive
2010/63/EC and institutional guidelines, were taken into consideration
in the present study. The animal experiments were approved by the State
Office for Agriculture, Food Safety and Fishery in Mecklenburg-Western
Pomerania (LALFF M-V) under reference numbers LALLF 7221.3-1.1-064/17
and LALLF 7221.3-2-011/19.