Body and splenic weights
The body weights of the animals were carefully monitored. Only slight
changes in the weights from Day 0 to Day 28 were seen and may be
attributed to differences in the metabolic activity of the animals (data
not shown). The spleen weights (collected on Day 28) were measured to
assess their in vivo immunomodulatory status following
administration of antigen (OVA) in the presence or absence ofMorus alba L. or CT treatments. A significant increase in the
spleen weights was seen following treatment with OVA and Morus
alba L. or CT and Morus alba L. compared to the OVA alone group
(Fig 2A).