Mortality
To evaluate the potency of Morus alba L.-induced immune responses
against a lethal infection with influenza virus, vaccinated mice were
challenged with mouse-adapted H1N1 influenza A subtypes. The protective
efficacies were measured by survival rates monitored every day for 14
days. As shown in Fig. 6B, Morus alba L. adjuvants enhanced mouse
survival rates post-challenge with a single-dose of HA vaccine. The
protective efficacy of the non-adjuvanted vaccine was only 50%.
However, mice given Morus alba L. adjuvant were protected against
the viral challenge.