Pathology slides
  1. Figure 1. High magnification image of H&E stained slide showing lymphoid tissue composed of small lymphocytes with scattered megakaryocytes (arrows) and clusters of myeloid and erythroid cells (circled)
  2. Figure 2. Immunohistochemical stain “CD61”, highlighting the cytoplasm of megakaryocyte in brown chromogen and confirming the lineage.
  3. Figure 3. Immunohistochemical stain “MPO”, highlighting the myeloid precursors.
  4. Figure 4. Immunohistochemical stain “Hemoglobin A”, highlighting the erythroid precursors
Radiology images
  1. Sagittal T2 WI of the LSS shows diffuse low signal intensity of the bone marrow of LSS ( known case of thalassemia major) with well-defined mass of the same signal intensity (5.3 x 3 cm) in presacral region (blue arrow) and another similar smaller mass (2x 1 cm) in anterior extradural space posterior to S1 level (Blue arrow)
  2. Axial post contrast fat saturated image at presacral region shows mild enhancement of the presacral mass (Blue arrow). No definite infiltration of the sacrum.
  3. Axial post contrast fat saturated image at S1 level shows mild enhancement of anterior extradural mass (blue arrow) at the midline laterally displacing S1 traversing nerve roots.