Statistical analysis
Study data were gathered and managed using REDCap electronic data capture tools hosted at Urooncology Association Turkey (17,18).  REDCap (Research Electronic Data Capture) is a secure, web-based software platform designed to support data capture for research studies. The T-test, Mann-Whitney U test and Chi-square test were used to analyze the relationship of categorical and continuous variables between two biopsy methods and three biopsy schemes of the combined biopsy method. A p value less than 0.05 were considered statistically significant.