What is known?
MRI targeted biopsies are reported to be able to better detect high grade cancers than systematic biopsies and TRUS. However, several recent studies have reported a mismatch in the biopsy and radical prostatectomy Gleason Score. Despite the improved detection of clinically significant cancers with MRI targeted biopsies, considerable disparity exists in the literature regarding MRI targeted biopsy’s ability to better detect RP pathology in biopsy-naive men over conventional TRUS biopsies.